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KMID : 0356719960120020247
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Journal of the Korean Society of Coloproctology
1996 Volume.12 No. 2 p.247 ~ p.252
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Colorectal Carcinoma in Patient Less Than 40 Years Old -Clinico-pathology and prognosis-
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Woo Jae-Hong
Cha Young-Kyu
Yoon Seo-Koo
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Abstract
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Several prior studies have shown that the prognosis of young adult patients with colorectal cancer is poor. A comparative clinical study was performed in 69 patients diagnosied below the age of 40 and a control group of 462 patients aged 40 or older. Chisquare test and unpaired t test were used to compare differences in distribution. The survival of each patient was studied by Kaplan-Meier method, and statistical analysis was done with the generalized Wilcoxon test: P<0.05 was considered statistically significant. Colorectal cancer in the young patients under the age of 40 was found to
have a relatively higher incidence of peritoneal dissemination(20.3%, p=0.0818). and a significant higher incidence of mucinous lesion(24.3%, p<0.0001) and neighboring organ invasions(22.5%, p=0.0127). There were no significant differences between the two groups with regard to sex distribution, duration of symptom, tumor site, tumor site, tumor stage, rate of hepatic metastasis or rate of lymphnode metastasis. The long term survival rate for the younger group was close to that for the older control group. This findings indicate the importance of early diagnosis and aggressive surgical resection for
improvement of the prognosis of patients under the age of 40.
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KEYWORD
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Colorectal Neoplasms, Young Adults
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